Summary: Single-cell transcriptomics suffer from sensitivity limits that restrict low abundance transcript identification, affects clustering and can hamper downstream analyses.Here, we describe Constellation sequencing (Constellation-Seq), a molecular transcriptome filter that delivers two orders of magnitude sensitivity gains by maximizing read u
Loss-of-heterozygosity on chromosome 19q in early-stage serous ovarian cancer is associated with recurrent disease
Abstract Background Ovarian cancer is a heterogeneous disease and prognosis for apparently similar cases of ovarian cancer varies.Recurrence of the disease in early stage (FIGO-stages Food Service:Refrigeration Equipment:Commercial Freezers I-II) serous ovarian cancer results in survival that is comparable to those with recurrent advanced-stage dis
Late-Stage Diagnosis of Breast Cancer in Brazil: Analysis of Data from Hospital-Based Cancer Registries (2000-2012)
Abstract Objective To analyze the time trend and the factors regarding the diagnosis of latestage breast cancer in Brazil from 2000 to 2012.Methods We conducted a retrospective cohort study using data from hospital-based cancer registries.Joinpoint regression was used to analyze the time trends of stage at diagnosis.The risk of Antenna Extension la
The Construction of Spin Foam Vertex Amplitudes
Spin foam vertex amplitudes are the key ingredient of spin foam models for quantum gravity.These fall into the realm of discretized path integral, and can be seen as generalized lattice gauge theories.They can be seen as an attempt at a 4-dimensional generalization of the Food Service:Refrigeration Equipment:Commercial Freezers Ponzano-Regge model